Vitamin B12 (Cobalamin)

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Vitamin B12 (Cobalamin)


Test Description

Vitamin B12 is a vital vitamin for various bodily functions such as blood cell production, brain health, and proper functioning of the nerve.
The vitamin B12 test will check levels of your:

  • Overall vitamin B12
  • Homocysteine
  • holotranscobalamin (holoTC)
  • methylmalonic acid (MMA)
  • Low B12 levels can result in permanent nerve damage, memory loss, temporary infertility in women and deteriorating brain functions. People who eat too much meat or are obese also tend to have higher levels of B12. High vitamin B12 levels can be an indication of liver disease, diabetes or certain types of leukemia.
    When to Order a Vitamin B12 Test?

    Your healthcare practitioner might suggest a B12 test if you have:
  • Tingling in the feet and hands
  • Problems with balance
  • Confusion
  • Dementia
  • A racing heart
  • Weakness
  • You may even ask to order this test if your healthcare practitioner suspects that you might have pernicious anemia. Pernicious anemia is a decline in red blood cells. It happens when your intestines aren’t able to absorb vitamin B12 that’s essential for red blood cell production. Signs aren’t generally seen in those younger than 30 years old. And 60 is the average diagnosis age.
    Symptoms of this health condition are:
  • Loss of appetite
  • Exhaustion
  • Pale skin
  • Constipation or diarrhea
  • Bleeding gums or inflamed red tongue
  • Your healthcare practitioner may also recommend ordering vitamin B12 test if you have high serum folate levels. High serum folate levels may indicate a deficiency of vitamin B12 and worsen the condition symptoms. Serum folate determines the folic acid level in the body. Folic acid is essential for the growth and development of your body and the production of white and red blood cells as well as platelets.
    Who You Should Order a B12 Test?
    Your body doesn’t produce B12 naturally. It obtains from animal products such as meat, fish, and dairy. Those who are at risk for B12 deficiency are:
  • Older adults
  • Vegans
  • Children
  • Strict vegetarians
  • People with diabetes
  • People who have had gastric bypass surgery
  • New mothers who are in the period of breastfeeding might be suggested to order a vitamin B12 test to check B12 levels if they show signs.
    Interpreting the B12 Test Results
  • Normal: The normal range for B12 in the blood is 200 to 900 ng/mL
  • Low: B12 levels are low if they are below 200 ng/mL. This test result indicates a B12 deficiency, an overactive thyroid or pernicious anemia
  • High: An abnormally high B12 status is over 900 ng/mL. This test result indicates kidney or liver problems, certain types of leukemia or diabetes
  • Even though it isn’t mandatory to fast before a B12 test, an individual may need to if his or her healthcare practitioner is also using this test to check other components in the blood. It is also important that a person tell their healthcare practitioner about any supplements and drugs they are taking as some can affect the test results.
    Testing Info

    Alternate Name: B12, Cobalamin, Cyanocobalamin

    Test Instructions : Please do not exercise prior to testing. It is best that your blood is taken in a rested state.

    Fasting: No

    Methodology: Immunoassay (IA)

    Results In: 2

    Note: Turn around times on results are an estimate and are not guaranteed. The lab may need additional time due to holidays, confirmation/repeat testing, etc. You can contact us to discuss when your results should be ready and we will contact the lab on your behalf immediately.